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P. 679
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VABIATIOXS IN THE BLOOD, AND IN ITS DISTRIBUTION. 689
of which have been absorbed by the M'hite corpuscles." It is known
that in heakh there is a continuous consumption of the red corpus-
cles of the blood, and it is probable that the essential phenomenon
of this disease is an exaggeration of this function, and that the con-
sumption exceeds the powers of regeneration. This consumption is
supposed to take place in the liver, but it is also known that under
certain circumstances the red globules are destroyed by the white, and
that these may become temporarily stained. This leads to the supposi-
tion that these corpuscles may be of that character. The place of the
formation of the red blood-corpusclfs is not certainly known. This
function has been attributed to the spleen, to the lymphatic glands, and
to the marrow of the bones. The bone-
marrow seems to have been found in a Fig. 383.
diseased state in many cases of anaemia,
and under these circumstances cells very
like the red blood-globules have been dis-
covered (Fig. 383).
Chlorosis is a form of anaemia seen in
females at or about the age of puberty.
It is supposed to be due to a deficiency
ill the formation of the red blood-corpus-
^^^.^ ^^^ ,j^^^,ii^ „, b^^^ .^ p^^.
cles, and is verv amenable to treatment nicious Ancemia: «, uucieated red
• ,1,1 ", /. . -fTT'.i ,1 • corpuscles; c, a red corpuscle with
M'ltll the preparation Ot iron. With this grauular nucleus; />, large nucleated
condition there is often associated some ^"''' ""''' ^'''''*
'iow "jToo)!'
deficiency in the vascular system, such as
narrowness of the aorta or some of the important blood-vessels. Con-
trary to what is usually seen in the other forms of anaemia, the body
seems well nourished in chlorosis, but there is the same defect in the
proportion of the red blood-globules. The flesh, however, is usually
soft and flabby, and a disposition to oedema is manifest in the extrem-
ities. Chlorotic patients are more than usually liable to nervous
disorders.
In all these forms of anaemia the diminution of the coloring matter
of the blood appears to be the prime factor, and cases of marked cha-
racter now and then occur in which this deficiency is very marked,
while the number of the corpuscles remains normal or nearly so. The
bulk of the blood is not necessarily diminished, but may be more watery
than normal, and may not clot so readily. This often gives rise to
difficulty in controlling hemorrhage. Secondary changes in the tissues,
especially in the form of fatty degenerations, may occur in any of the
forms of anaemia from the imperfect nutrition of the tissues. Inflam-
matory processes are languidly performed, and are more prone to run a
chronic course. The treatment of alveolar abscess, diseased pulps of
teeth, or any of the inflammatory diseases of the mouth or other parts
is rendered more uncertain and difficult.
Local ancemia is the diminution of the blood of a part. It is prob-
able that this occurs in various organs as a feature of the neuroses or
as perversions of innervation. There seems to be such a thing as a
tonic spasm of the arteries of a part or organ, during the continuance
of which the amount of blood admitted to it is materially lessened.
Vol. l.—U
VABIATIOXS IN THE BLOOD, AND IN ITS DISTRIBUTION. 689
of which have been absorbed by the M'hite corpuscles." It is known
that in heakh there is a continuous consumption of the red corpus-
cles of the blood, and it is probable that the essential phenomenon
of this disease is an exaggeration of this function, and that the con-
sumption exceeds the powers of regeneration. This consumption is
supposed to take place in the liver, but it is also known that under
certain circumstances the red globules are destroyed by the white, and
that these may become temporarily stained. This leads to the supposi-
tion that these corpuscles may be of that character. The place of the
formation of the red blood-corpusclfs is not certainly known. This
function has been attributed to the spleen, to the lymphatic glands, and
to the marrow of the bones. The bone-
marrow seems to have been found in a Fig. 383.
diseased state in many cases of anaemia,
and under these circumstances cells very
like the red blood-globules have been dis-
covered (Fig. 383).
Chlorosis is a form of anaemia seen in
females at or about the age of puberty.
It is supposed to be due to a deficiency
ill the formation of the red blood-corpus-
^^^.^ ^^^ ,j^^^,ii^ „, b^^^ .^ p^^.
cles, and is verv amenable to treatment nicious Ancemia: «, uucieated red
• ,1,1 ", /. . -fTT'.i ,1 • corpuscles; c, a red corpuscle with
M'ltll the preparation Ot iron. With this grauular nucleus; />, large nucleated
condition there is often associated some ^"''' ""''' ^'''''*
'iow "jToo)!'
deficiency in the vascular system, such as
narrowness of the aorta or some of the important blood-vessels. Con-
trary to what is usually seen in the other forms of anaemia, the body
seems well nourished in chlorosis, but there is the same defect in the
proportion of the red blood-globules. The flesh, however, is usually
soft and flabby, and a disposition to oedema is manifest in the extrem-
ities. Chlorotic patients are more than usually liable to nervous
disorders.
In all these forms of anaemia the diminution of the coloring matter
of the blood appears to be the prime factor, and cases of marked cha-
racter now and then occur in which this deficiency is very marked,
while the number of the corpuscles remains normal or nearly so. The
bulk of the blood is not necessarily diminished, but may be more watery
than normal, and may not clot so readily. This often gives rise to
difficulty in controlling hemorrhage. Secondary changes in the tissues,
especially in the form of fatty degenerations, may occur in any of the
forms of anaemia from the imperfect nutrition of the tissues. Inflam-
matory processes are languidly performed, and are more prone to run a
chronic course. The treatment of alveolar abscess, diseased pulps of
teeth, or any of the inflammatory diseases of the mouth or other parts
is rendered more uncertain and difficult.
Local ancemia is the diminution of the blood of a part. It is prob-
able that this occurs in various organs as a feature of the neuroses or
as perversions of innervation. There seems to be such a thing as a
tonic spasm of the arteries of a part or organ, during the continuance
of which the amount of blood admitted to it is materially lessened.
Vol. l.—U
