Page 256 - My FlipBook
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:
THE MICRO-ORGANISMS OF THE HUMAN MOUTH. :
mouth, the question of their adaptability demands particular
consideration ; and in regard to this point I have examined a
number ofthe materials used in the treatment ofthe human mouth
in the same form and concentration as they may be made use of
in the form of a mouth-wash. Usually in rinsing the mouth the
solution remains from a few seconds to at most a minute in con-
nection with the mucous membrane and the teeth ; and we need
accordingly for the purpose of sterilizing the oral cavity a ma-
terial which in the adapted concentration is able to de^•italize
bacteria inside of a minute. How far this is accomplished by
the means at our command may be seen from the following
table
Antiseptic. Concentra- Time necessary
tion. for devitalization.
^Salicylic acid 1 : 100 \ minute
Listerine .... \ to I minute.
* Benzoic acid 1 : 100 i "
Salicylic acid 1 : 200 i "
Bichloride of mercury 1 : 2500 * to f "
Benzoic acid 1 : 200 1 to 2 minutes
Thymol .... 1 1 : 175 lto2 " "
Borobenzoic acid
: 1500
2 to 4
Bichloride of mercury 1 : 5000 2 to 5 "
Peroxide of hydrogen 10 per cent. 10 to 15 "
Carbolic acid 1 : 100 10 to 15 "
Oil of peppermint in agreeable s rength 5 to 10 "
Boric acid .... . 1 1 : 4000 more than 15 minutes
Permanganate of potash
: 50
"
15
"
Oil of wintergreen " " 15 "
Tincture of cinchona . 1 : 18 " " 15 "
Lime-water no action.
The above experiments were made in the following manner
A determined quantity of a pure culture of a ferment bacte-
rium of the mouth is brought into 0.5 c.cm. of the antiseptic to
be tested, and then in determined intervals single drops of this
mixture are brought into test tubes containing 5 c.cm. of a
nutritive solution. If a development of bacteria does not take
place in any tube or tubes, it may be taken as an indication that
the bacteria were devitalized in the corresponding time.
* Salicylic and benzoic acids may be applied in this concentration only on the
brush.
THE MICRO-ORGANISMS OF THE HUMAN MOUTH. :
mouth, the question of their adaptability demands particular
consideration ; and in regard to this point I have examined a
number ofthe materials used in the treatment ofthe human mouth
in the same form and concentration as they may be made use of
in the form of a mouth-wash. Usually in rinsing the mouth the
solution remains from a few seconds to at most a minute in con-
nection with the mucous membrane and the teeth ; and we need
accordingly for the purpose of sterilizing the oral cavity a ma-
terial which in the adapted concentration is able to de^•italize
bacteria inside of a minute. How far this is accomplished by
the means at our command may be seen from the following
table
Antiseptic. Concentra- Time necessary
tion. for devitalization.
^Salicylic acid 1 : 100 \ minute
Listerine .... \ to I minute.
* Benzoic acid 1 : 100 i "
Salicylic acid 1 : 200 i "
Bichloride of mercury 1 : 2500 * to f "
Benzoic acid 1 : 200 1 to 2 minutes
Thymol .... 1 1 : 175 lto2 " "
Borobenzoic acid
: 1500
2 to 4
Bichloride of mercury 1 : 5000 2 to 5 "
Peroxide of hydrogen 10 per cent. 10 to 15 "
Carbolic acid 1 : 100 10 to 15 "
Oil of peppermint in agreeable s rength 5 to 10 "
Boric acid .... . 1 1 : 4000 more than 15 minutes
Permanganate of potash
: 50
"
15
"
Oil of wintergreen " " 15 "
Tincture of cinchona . 1 : 18 " " 15 "
Lime-water no action.
The above experiments were made in the following manner
A determined quantity of a pure culture of a ferment bacte-
rium of the mouth is brought into 0.5 c.cm. of the antiseptic to
be tested, and then in determined intervals single drops of this
mixture are brought into test tubes containing 5 c.cm. of a
nutritive solution. If a development of bacteria does not take
place in any tube or tubes, it may be taken as an indication that
the bacteria were devitalized in the corresponding time.
* Salicylic and benzoic acids may be applied in this concentration only on the
brush.
