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SULPHATE OF QUININE. 537

For Itijlained Gums and Mucous Digest for six days and filter.
Alevibrane. SiGNA.—To be used as a gargle or
mouth wash.
Prof. Chapin A. Harris.
Mouth Wash.
R . Quillaire saponarire S^i'J
Dr. \V. H. Fdwler.
Pyrethri,
Radicis iridis, R . Fluid Ext. Soap Tree
Acidi benzoici, Bark l^^Yz
Cinnamomi . . . iia l\ Alcohol 5 ss
Acidi tannici . . p^iv Glycerine _^jss
.
Sodii boratis . . . ^iv Haniamelis (Pond's
Olei gaultherize . f.^ij Extract) _^iij
Olei menthae . . . f ^iv Oil of wintergreen . . tTtviij
Cochineal 3"J Oil of cloves .... TTLv
Saccliari albi . . . Ibj Soft water ^ viij.
Alcoholis Oiij Dissolve the oils in the alcohol and
Aquae purse .... . Ov. M. then add the other ingredients.

QUININ.^ SULPHAS—SULPHATE OF QUININE.

Derivation.—The two important alkaloid principles of cin-
chona are quinia and cinchonia., which exist in combination with
kinic acid. (See Cinchona.)
Sulphate of Quinine is obtained by boiling the powdered
yellow cinchona bark in water acidulated with hydrochloric acid,
bv which the alkaloid quinine is separated from kinic and other
acids, and forms a soluble hydrochlorate or muriate, the salt be-
ing decomposed and the quinine precipitated by the addition of
lime ; sulphuric acid is added, after digestion in boiling alcohol,
which dissolves the quinine, and the solution is boiled with ani-
mal charcoal, filtered and allowed to crystallize. Sulphate of
quinine is in the form of colorless, very light and silky crystals,
which are readily soluble in alcohol and in water acidulated with
sulphuric acid, but insoluble in ether. It has an intensely bitter
taste, and is inodorous.
Medical Properties and Action.—Sulphate of quinine is a very
valuable tonic and antiperiodic, also antiseptic and stimulant. In
small doses it increases the fullness of the pulse and action of
the heart, and improves the tonicity of the capillary vessels, and
is diffused into various parts of the system with great rapidity.