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698 GENERAL PATHOLOGY.

their characteristic stellate or caudate outline and are converted into irreg-
ular clumps. If the cornea is exam-
ined in this stage after treatment with Fig. 389.
chloride of gold, it is seen that in ^W.
those parts in which the structural p "^
changes are most advanced the nor- B
mal character of the tissue is entirely Br
lost (Fig. 389). The beautiful net-
work produced by the interlacing of Wf:
the normal corpuscles is no longer k
^
visible ; in place of it the field is scat-
^
tered over with clumps of irregular
form, in some of which the caudse are F
represented by rounded knobs, while m
in others the outlines are almost sphe- |r
roidal. Most of these bodies are so t^
Altered Corpuscles of the Cornea, excised
gidiuuar inai ineu^ COnrenih Cannoi Oe
crrnnnlir tlint tlipir r-nntpnts! r-nnnnf Iip
gj^jj^t jjo^j.^ after irritation (Sanderson).
distinguished, but in others the newly-
formed germs are plainly visible. The number of these germs varies
according to the stage of irritation, so that in the same cornea clumps
containing a numerous offspring may be seen in one part, while in others
the germination is only beginning (Figs. 390, 391).
" That the interpretation suggested by these appearances is the true
one, that the clumps containing numerous round corpuscles are nearly
Fig. 390. Fig. 391.


















Cornea, sixteen hours after irritation: anioe- Cornea, ahout twenty-four hours after the iiiser-
lioid luasses containing numerous newly- tion of a fine ligature: masses containing
formed elements (Sanderson). young elements in the neighborhood of the
thread (.Sanderson).
of the nature of mother-cells, the observer can best assure himself by
returning to the method of examination first described ; that is to say,
by placing the inflamed tissue under the microscope alive, at the same
time stimulating the elements in question to increased amoeboid move-
ment by irrigation with serum. It is tiien seen that the germs chano-e
their relative ])osition Avith tlie movements of the mass of protoplasm in
whicii they are enclosed, just in tlie same way as the granules and
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